COVID-19 Vaccine Update as of August 2020

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Overview

Vaccine for any disease normally take years to develop. In Mar-Apr, Experts commented on the development of vaccine for Sars-CoV-2 to take 12-18 months. The earliest availability of vaccine for public was expected  to be mid-2021.  However, Russia is set to become the first country to launch vaccine for general public by September 2020.

doctor observing something with microscope

Scientists across the globe are working tirelessly to bring a cure to COVID-19.

In June 2020, a vaccine was approved in China for limited use only.

doctor in a lab with blood test tubes

Currently, there are over 175 global companies working on the vaccine for novel corona virus.

41 companies are said to be in advanced stage of clinical trials and 135 companies are currently in pre-clinical trial stage.

nurse preparing an injection

In a recent development, the 1st approved vaccine for public was announced by a Russian company – Gamaleya Institute for Epidemiology and Microbiology in collaboration with the Defense Ministry.

Companies in phase 3 of vaccine trials

How does the overall testing process work?

Overall Testing Process explained
Historical timeline chart of pandemic vaccine preparation

Vaccine preparation strategies

Type of VaccineProcedureUsed in treating other virusesCompanies working on corona virus Phase 3 trials
1.Whole-Virus Vaccines Inactivated and Live Attenuated VaccinesRequires growing virusesVaccines for influenza, chickenpox, measles, mumps and rubellaSinovac
Wuhan Institute of Biological Products / SinopharmBeijing Institute of Biological Products / Sinopharm
2.Genetic Vaccines RNA VaccinesDeliver mRNA for building a viral proteinNo approved vaccines;  under clinical trials for MERSModernaBioNTech / Fosun Pharma / Pfizer
3.Viral Vector Vaccines Vaccines Using Adenovirus or Other VirusesSpike protein gene to a virus known as adenovirus is slipped into cells to unload the geneVaccines for H.I.V. and Ebola are in Phase 3 trialsCanSinoUniversity of Oxford
4.Protein-Based Vaccines Recombinant VaccinesYeast or other cells can be engineered to carry a virus’s gene and spew out viral proteins, which are then harvested and put into a vaccineHepatitis BAnhui Zhifei Longcom Biopharmaceutical (currently in Phase 2 trials)

The Frontrunners in the vaccine race

Frontrunners in the vaccine race

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